Chemotherapy-Induced Peripheral Neuropathy

Peripheral neuropathy refers to symptoms arising from damage to peripheral nerves. These nerves carry sensation, control movements of the arms and legs, and control the bladder and bowel. Chemotherapy and other drugs used to treat cancer can cause peripheral neuropathy. This is termed chemotherapy-induced peripheral neuropathy (or CIPN).

Studies show Low-level laser light therapy (PBM)  may be a viable option for non-medical management of CIPN.

 

What Increases the Risk of Developing CIPN?

Certain chemotherapy drugs are more likely to cause neuropathy. These include: platinum drugs, such as oxaliplatin; taxanes, such as docetaxel; vinca alkaloids, such as vincristine; and myeloma treatments, such as bortezomib.

Other chemotherapy drugs can also cause neuropathy. The risk of developing CIPN is higher with higher doses, multiple courses, and combination chemotherapy. Patients are more likely to develop CIPN if they are older or have diabetes, vitamin deficiencies, or preexisting peripheral neuropathy.

How Can I Reduce My Risk of Developing CIPN?

No medication or supplement has been shown to definitively prevent CIPN. Regular exercise, reducing alcohol use, and treating preexisting medical conditions (vitamin B12 deficiency) may reduce the risk of CIPN.

What Are the Symptoms and Complications of CIPN?

Depending on the nerves affected, symptoms include:

  • Tingling (“pins and needles”)
  • Pain, which may be severe and constant, may come and go, or may feel like burning
  • Decreased sensation (“legs feel like jelly”)
  • Increased sensitivity to touch, temperature, pressure, pain
  • Muscle weakness

Symptoms can appear hours to days after chemotherapy and may reduce in intensity with time. Commonly, symptoms occur weeks to months after chemotherapy. They can get worse with additional cycles of chemotherapy.

At London Laser we want to help cancer Survivors improve their quality of life.  We offer several treatments to help deal with the side effects of cancer treatments. Check our Rise Up program for more details.

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